Conversion to Persistent or High-Risk Opioid Use After a New Prescription From the Emergency Departm


Led by PISC Executive Committee member Zachary F. Meisel, this study aimed to describe the overall risk and factors associated with transitioning to persistent opioid or high-risk use after an initial emergency department (ED) opioid prescription. After performing a retrospective cohort study of Washington Medicaid beneficiaries, it found that among 202,807 ED visits, 23,381 resulted in a new opioid prescription, and that 13.7% of such new prescriptions led to persistent or high-risk opioid prescription fills within 12 months. The results indicate that Medicaid recipients are at moderate risk, and that even visits that lead to guideline-concordant prescriptions can still potentially lead to long-term or high-risk use.

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