As the popularity of National Collegiate Athletic Association (NCAA) men's lacrosse increases, there is a greater need for injury surveillance that can help detect and mitigate emerging patterns of sport-related injury. Led by PISC trainee Bernadette D'Alonzo, MPH, and PISC Postdoctoral Fellow Abby Bretzin, PhD, this study collected injury data from a sample of men's lacrosse teams for the academic years of 2014 through 2019. After analysis, the study found that the overall injury rate was 4.90 per 1000 athlete exposures (AEs), and the competition injury rate was higher than the practice injury rate. It also found that the most reported injuries were concussions, ankle sprains, and hamstring tears, findings that were existing epidemiological evidence. In particular, the authors point out that the prevalence of concussions and lower extremity injuries may be an important issue to address in future studies.